The Temple Lung Center conducts one of the most comprehensive lung disease clinical trials programs in the country. Our advancements in basic, translational and clinical research are changing lung disease treatment. By pioneering effective therapies, we bring hope to patients with serious and debilitating lung diseases.
Review Our Open Clinical Trials
Asthma
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
NCT05097287
NCT05097287
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
NCT05813288
NCT05813288
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/?Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
NCT06052267
NCT06052267
Pragmatic Open - Label Randomized Clinical Trial of FF/?UMEC/?VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma
Bronchiectasis
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
NCT06559150
COPD
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
NCT05119556
NCT05119556
Temple Health Chest Initiative (THCI 2.0) - Lung Cancer Screening Project With COPD Detection
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema (ELEVAATE OLE)
NCT05897424
NCT05897424
A Study to Assess the Effects of Dexpramipexole in Participants with Eosinophilic COPD (SUSPIRE-1)
NCT06533553
NCT06533553
STRIVE Post-Market Registry Study
NCT04302272
NCT04302272
PH-COPD MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035
NCT05612035
Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial) (DEPTH)
NCT05382208
NCT05382208
Inpatient Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
NCT06175065
NCT06175065
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
Biological Effects of Quercetin in COPD Phase II
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)
A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)
Interstitial Lung Disease (ILD)
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease (BEconneCTD-ILD)
NCT06572384
A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
NCT06335303
A Study to Test Whether BI 1839100 Improves Cough in People With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis
NCT06360094
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
NCT05943535
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis (TETON)
NCT04708782
NCT04708782
SSc-ILD A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (BLISSc-ILD)
NCT05878717
NCT05878717
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients (EGCG-101)
NCT05195918
NCT05195918
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis
A Study Evaluating the Safety and Efficacy of AP01 in Participants With Progressive Pulmonary Fibrosis (PPF)
NCT06329401
NCT06329401
Platform Clinical Study for Conquering Scleroderma (CONQUEST)
NCT06195072
A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
NCT06317285
NCT06317285
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
NCT05975983
Inpatient
Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)
Lung Cancer
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening (PROACT-LUNG)
Lung Transplant
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction (ROCKaspire)
Mesothelioma
National Mesothelioma Virtual Registry and Tissue Bank (U19)
Mycobacterium Avium Complex Disease
ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension (ICoN-1)
Pulmonary Vascular Disease
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
NCT04798261
Novel alpha2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial (NAIL-IT)
NCT05408546
NCT05408546
PH-COPD MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035
Sarcoidosis
Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis (KITE)
Other
American Lung Association (ALA) Lung Health Cohort
NCT04543461
NCT04543461