
The Temple Lung Center conducts one of the most comprehensive lung disease clinical trials programs in the country. Our advancements in basic, translational and clinical research are changing lung disease treatment. By pioneering effective therapies, we bring hope to patients with serious and debilitating lung diseases.
Review Our Open Clinical Trials
Asthma
ALA-ACRC "Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma" (MATCH) Trial
A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype
NCT04718103
NCT04718103
Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States (PASSAGE)
NCT05329194
NCT05329194
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
NCT05097287
NCT05097287
Bronchiectasis
Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population (HFCWO)
COPD
A Multi-center, Randomized, Double-blind, Parallel-group, Placebo-controlled Study of Mepolizumab 100mg SC as add-on Treatment in Participants With COPD Experiencing Frequent Exacerbations and Characterized by Eosinophil Levels (MATINEE)
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312
NCT04069312
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (RESOLUTE)
NCT04053634
NCT04053634
Evaluation of the Safety and Efficacy of TLD in Patients With COPD (AIRFLOW-3)
NCT03639051
NCT03639051
Predicting Sleep, Smoking, and Lung Health Disparities in African American Adults
NCT03534076
NCT03534076
A Sham Controlled Prospective Randomized Clinical Trial of the RejuvenAir System for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease with Chronic Bronchitis (Spray-CB)
NCT03893370
NCT03893370
Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis (RheSolve)
NCT04677465
NCT04677465
Immunological Basis for Benralizumab Activity in Chronic Obstructive Pulmonary Disease (COPD)
NCT05273359
NCT05273359
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
NCT05119556
NCT05119556
Immunological Basis for Mepolizumab Activity in COPD
NCT05320939
NCT05320939
STRIVE Post-Market Registry Study
NCT04302272
NCT04302272
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NCT05204888
NCT05204888
Functional Lung Imaging in Patients with Respiratory Compromise Undergoing Endobronchial Valve Placement
NCT05204875
NCT05204875
Efficacy and Safety of Tozorakimab (MEDI3506) in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations. (TITANIA)
NCT05158387
NCT05158387
A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
NCT05037929
NCT05037929
MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035
NCT05612035
Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial) (DEPTH)
NCT05382208
NCT05382208
Interstitial Lung Disease (ILD)
A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs)
Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis (IPF-COMFORT)
NCT05185089
NCT05185089
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis (GKT137831)
NCT03865927
NCT03865927
Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial (PRECISIONS)
NCT04300920
NCT04300920
Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis (TETON)
NCT04708782
NCT04708782
A Randomized, Double Blind, Placebo-controlled, study to investigate the safety, pharmacokinetics and pharmacodynamics of CSL312 in Subjects with Idiopathic Pulmonary Fibrosis
NCT05130970
NCT05130970
A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (BLISSc-ILD)
NCT05878717
NCT05878717
Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis (REVERT-IPF)
NCT05671835
NCT05671835
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients (EGCG-101)
NCT05195918
NCT05195918
Inpatient
Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)
Lung Cancer
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
Neoadjuvant Use of Aliya Pulsed Electric Fields with Systemic Therapy in Early-stage Resectable Non-Small Cell Lung Cancer (NSCLC)
Mycobacterium Avium Complex Disease
Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)
Pulmonary Embolism
The PEERLESS Study (PEERLESS)
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
Sarcoidosis
Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis
A Study to Assess the Efficacy and Safety of Namilumab in Participants With Chronic Pulmonary Sarcoidosis (RESOLVE-Lung)
NCT05314517
Other
American Lung Association (ALA) Lung Health Cohort
NCT04543461
NCT04543461
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE (ASTER)