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Temple Lung Center | Enrolling Clinical Trials
The Temple Lung Center conducts one of the most comprehensive lung disease clinical trials programs in the country. Our advancements in basic, translational and clinical research are changing lung disease treatment. By pioneering effective therapies, we bring hope to patients with serious and debilitating lung diseases.
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Temple Lung Center Performs First Procedure in AIRFLOW-4 Clinical Trial for COPD
The Temple Lung Center has performed the first procedure in the AIRFLOW-4 clinical trial, evaluating the investigational dNerva® Lung Denervation System — a novel, non-implant, bronchoscopic therapy designed to target the underlying neural drivers of COPD symptoms. Patient enrollment is currently underway.
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FAQ: Building and Scaling a High-Performance Lung Transplant Program
Lung transplantation remains one of the most complex, resource-intensive interventions in pulmonary medicine, requiring precise coordination across disciplines, rapid evaluation pathways, and long-term patient management strategies.
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Temple Lung Center at ATS 2026: Conference Recap
The American Thoracic Society's 2026 International Conference brought together leading voices in pulmonary, critical care, and sleep medicine — and Temple Health was well represented.
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Temple Lung Center Joins National Bronchiectasis and NTM Care Center Network
Temple Lung Center is proud to announce its official designation as a member of the Bronchiectasis and NTM Care Center Network, a national collaborative dedicated to advancing research, improving standards of care, and expanding access to specialized treatment for patients living with bronchiectasis and nontuberculous mycobacterial (NTM) lung disease.
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Temple Lung Center: Advances in Lung Care and Research in 2025
Pulmonary care is evolving rapidly, from earlier detection strategies to new minimally invasive therapies and expanding access to clinical trials.
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COPD Clinical Trials at Temple Lung Center
Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity, and many patients continue to experience symptoms despite optimal therapy. As one of the world’s largest and most experienced COPD research programs, the Temple Lung Center offers access to clinical trials evaluating new pharmacologic, device-based, and comprehensive treatment approaches.
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2025 GOLD International COPD Conference
Hosted in partnership by The Temple Lung Center and the Global Initiative for Chronic Obstructive Lung Disease (GOLD), this conference will be presented in a hybrid format with in-person sessions virtually simulcast to a global audience of healthcare providers involved in the care and management of people with COPD. Learn alongside other dedicated COPD practitioners, and hear directly from leading experts and researchers.
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Lung Transplant Program Referral Information
The Temple Lung Transplant Program is a leader in both quantity and quality. It’s the nation’s highest volume program, but it also has the best one-year survival rates in Philadelphia and all of Pennsylvania.
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Diagnosis and Treatment of Obesity-Hypoventilation Syndrome
Obesity hypoventilation syndrome (OHS) is a respiratory disorder resulting in multisystem dysfunction. This program will review the epidemiology, pathophysiology, and mortality of this disorder. Current treatment recommendations as put forth by the American Thoracic Society Assembly on Sleep and Respiratory Neurobiology will be presented, including a comprehensible treatment algorithm.
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Bronchoscopic Lung Volume Reduction in Patients with Advanced Emphysema
As part of the Pulmonology On Air 2022 Global Event, Gerard Criner, MD, FACP, FACCP, Director of the Temple Lung Center, demonstrates a LIVE endobronchial valve placement on a patient with advanced homogenous emphysema.
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COVID Pneumonia
"COVID pneumonia represents the active inflammation of the pulmonary parenchyma that is caused by SARS-CoV-2, the coronavirus that has caused the COVID-19 pandemic. Millions of patients have been affected worldwide and hospitalizations have occurred all over the globe. The condition can range from mild to severe and represents a challenge for clinicians. Despite the above there is still significant morbidity and mortality associated with COVID pneumonia. It is important for clinicians to recognize this entity, and follow closely the rapidly changing recommendations regarding management and treatment."